Publications

Methodological research in biostatistics and software implementation

  1. Feng, C. , Sugier, P. E. , Zou, N. , Liquet, B. (2026). A Guide for Exploring Pleiotropic Associations in Genome-Wide Association Studies using Summary Statistics . Statistics in Medicine .
  2. Sugier, P.-E. , Asgari, Y. , Sedki, M. , Truong, T. , Liquet, B. (2025). Meta-analysis models with group structure for pleiotropy detection at gene and variant level using summary statistics from multiple datasets . Biostatistics , 26(1): kxaf037 .
  3. Asgari, Y. , Sugier, P.-E. , Baghfalaki, T. , Lucotte, E. , Karimi, M. , Sedki, M. , et al. (2023). GCPBayes pipeline: a tool for exploring pleiotropy at the gene level . NAR Genomics and Bioinformatics , 5(3): lqad065 .
  4. Baghfalaki, T. , Sugier, P.-E. , Asgari, Y. , Truong, T. , Liquet, B. (2023). GCPBayes: An R package for studying Cross-Phenotype Genetic Associations with Group-level Bayesian Meta-Analysis . The R Journal , 15(1): 122--141 .
  5. Sutton, M. , Sugier, P.-E. , Truong, T. , Liquet, B. (2022). Leveraging pleiotropic association using sparse group variable selection in genomics data . BMC medical research methodology , 22(1): 9 .
  6. Baghfalaki, T. , Sugier, P.-E. , Truong, T. , Pettitt, A. N. , Mengersen, K. , Liquet, B. (2021). Bayesian meta-analysis models for cross cancer genomic investigation of pleiotropic effects using group structure . Statistics in medicine , 40(6): 1498--1518 .

Applications of advanced statistical methods

  1. Domenighetti, C. , Sugier, P.-E. , Sreelatha}, A. {. K. , Schulte, C. , Grover, S. , Portugal, B. , et al. (2024). Association of body mass index and Parkinson disease: a bidirectional mendelian randomization study . Neurology , 103(3): e209620 .
  2. Lucotte, E. A. , Asgari, Y. , Sugier, P.-E. , Karimi, M. , Domenighetti, C. , Lesueur, F. , et al. (2024). Investigation of common genetic risk factors between thyroid traits and breast cancer . Human molecular genetics , 33(1): 38--47 .
  3. Sugier, P.-E. , Lucotte, E. A. , Domenighetti, C. , Law, M. H. , Iles, M. M. , Brown, K. , et al. (2023). Investigation of shared genetic risk factors between Parkinson's disease and cancers . Movement disorders , 38(4): 604--615 .
  4. Guibon, J. , Sugier, P.-E. , Kulkarni, O. , Karimi, M. , Bacq-Daian, D. , Besse, C. , et al. (2021). Fine--mapping of two differentiated thyroid carcinoma susceptibility loci at 2q35 and 8p12 in Europeans, Melanesians and Polynesians . Oncotarget , 12(5): 493--506 .
  5. Kulkarni, O. , Sugier, P.-E. , Guibon, J. , Boland-Augé, A. , Lonjou, C. , Bacq-Daian, D. , et al. (2021). Gene network and biological pathways associated with susceptibility to differentiated thyroid carcinoma . Scientific Reports , 11(1): 8932 .
  6. Sugier, P.-E. , Sarnowski, C. , Granell, R. , Laprise, C. , Ege, M. J. , Margaritte-Jeannin, P. , et al. (2019). Genome-wide interaction study of early-life smoking exposure on time-to-asthma onset in childhood . Clinical \& Experimental Allergy , 49(10): 1342--1351 .
  7. Sugier, P.-E. , Brossard, M. , Sarnowski, C. , Vaysse, A. , Morin, A. , Pain, L. , et al. (2018). A novel role for ciliary function in atopy: ADGRV1 and DNAH5 interactions . Journal of Allergy and Clinical Immunology , 141(5): 1659--1667 .
  8. Sarnowski, C. , Sugier, P.-E. , Granell, R. , Jarvis, D. , Dizier, M.-H. , Ege, M. , et al. (2016). Identification of a new locus at 16q12 associated with time to asthma onset . Journal of Allergy and Clinical Immunology , 138(4): 1071--1080 .

Other applications

  1. Gálvez-Navas, J. M. , Peruchet-Noray, L. , Molina-Montes, E. , Rodríguez-Barranco, M. , Biessy, C. , Antoniussen, C. S. , et al. (2026). One-carbon metabolism nutrients and polygenic risk scores in relation to breast cancer risk: A nested case-control study within the EPIC cohort . The American Journal of Clinical Nutrition , 101456 .
  2. Mandle, H. B. , Jenab, M. , Gunter, M. J. , Tjønneland, A. , Olsen, A. , Dahm, C. C. , et al. (2025). Inflammation and gut barrier function-related genes and colorectal cancer risk in western European populations . Mutagenesis , 40(1): 48--60 .
  3. Park, S. H. , Sugier, P.-E. , Asgari, Y. , Karimi, M. , Kaaks, R. , Fortner, R. T. , et al. (2025). Reproductive factors, sex hormone levels, and differentiated thyroid cancer risk: a Mendelian randomization study . Thyroid , 35(4): 433--443 .
  4. Domenighetti, C. , Sugier, P.-E. , Sreelatha}, A. {. K. , Schulte, C. , Grover, S. , Mohamed, O. , et al. (2022). Dairy intake and Parkinson's disease: a Mendelian randomization study . Movement Disorders , 37(4): 857--864 .
  5. Grover, S. , Sreelatha}, A. A. {. , Pihlstrom, L. , Domenighetti, C. , Schulte, C. , Sugier, P.-E. , et al. (2022). Genome-wide association and meta-analysis of age at onset in Parkinson disease: evidence from the COURAGE-PD consortium . Neurology , 99(7): e698--e710 .
  6. Domenighetti, C. , Sugier, P.-E. , Sreelatha, A. A. K. , Schulte, C. , Grover, S. , Mohamed, O. , et al. (2022). Mendelian randomisation study of smoking, alcohol, and coffee drinking in relation to Parkinson’s disease . Journal of Parkinson’s disease , 12(1): 267--282 .
  7. Liu, H. , Dehestani, M. , Blauwendraat, C. , Makarious, M. B. , Leonard, H. , Kim, J. J. , et al. (2022). Polygenic resilience modulates the penetrance of Parkinson disease genetic risk factors . Annals of neurology , 92(2): 270--278 .
  8. Domenighetti, C. , Douillard, V. , Sugier, P.-E. , Sreelatha, A. A. K. , Schulte, C. , Grover, S. , et al. (2022). The interaction between HLA-DRB1 and smoking in Parkinson's disease revisited . Movement Disorders , 37(9): 1929--1937 .
  9. Domenighetti, C. , Douillard, V. , Sugier, P.-E. , Vince, N. , Elbaz, A. , {others}, (2022). Une valine 11 codée par le gène HLA-DRB1 est associée inversement au risque de maladie de Parkinson et interagit avec l’initiation du tabagisme . Revue neurologique , 178: S15 .
  10. Truong, T. , Lesueur, F. , Sugier, P.-E. , Guibon, J. , Xhaard, C. , Karimi, M. , et al. (2021). Multiethnic genome-wide association study of differentiated thyroid cancer in the EPITHYR consortium . International journal of cancer , 148(12): 2935--2946 .
  11. Grover, S. , Kumar-Sreelatha, A. A. , Bobbili, D. R. , May, P. , Domenighetti, C. , Sugier, P.-E. , et al. (2021). Replication of a novel Parkinson's locus in a European ancestry population . Movement Disorders , 36(7): 1689--1695 .
  12. Mencke, P. , Hanss, Z. , Boussaad, I. , Sugier, P.-E. , Elbaz, A. , Krüger, R. (2020). Bidirectional relation between Parkinson's disease and glioblastoma multiforme . Frontiers in neurology , 11: 898 .
  13. Servy, A. , Maubec, E. , Sugier, P. , Grange, F. , Mansard, S. , Lesimple, T. , et al. (2016). Merkel cell carcinoma: value of sentinel lymph-node status and adjuvant radiation therapy . Annals of Oncology , 27(5): 914--919 .

preprint

  1. Landoulsi, Z. , Sreelatha, A. A. K. , Kuznetsov, N. , Schulte, C. , Bobbili, D. R. , Montanucci, L. , et al. (2025). Genome-wide association study of copy number variations in Parkinson’s disease . medRxiv , 2024--08 .
  2. Truong, T. , Park, S. H. , Asgari, Y. , Sugier, P.-E. , Karimi, M. , Thomsen, H. , et al. (2025). Large-scale association analysis identified novel differentiated thyroid carcinoma risk loci by integrating transcriptome and proteome . HAL .